CTQ-020 Organic Synthesis (4-0-4)

Code: CTQ-020

 

Title: Organic Synthesis

 

Level: Master / PhD

Mandatory: no

Total study time: 96h                                                   TPI: (4-0-4)

 

Summary:

Organic function selectivity and use of protection groups in preparative Organic Chemistry; polarity inversion. Organic synthesis based in name reactions. Retrosynthetic analysis principles. Disconnections, synthon concept and synthetic equivalents. Strategies applied on the multistep preparation of organic compounds. Natural products synthesis, biomolecules and compounds with biological activity. Applying retrosynthetic analysis on the design of organic compounds synthesis.

 

Bibliography

• Carey, F. A. A.; Sundberg, R. J., Advanced Organic Chemistry, Part B: Reaction and Synthesis, 4^th edition, Springer-Verlag (LLC), 2001.
• Kürti, L.; Czakó, B., Strategic Applications of Named Reactions in Organic Synthesis, Elsevier, 2005.
• Wyatt, P.; Warren, S., Organic Synthesis: Strategy and control, Wiley and Sons, 2007.
• Warren, S.; Wyatt, P., Organic Synthesis: The disconnection approach, 2^nd edition, Wiley and Sons, 2009.

Complementary Bibliography

• Schreiber, S. L.; Kapoor, T. M.; Wess, G. (Eds), Chemical Biology: From Small Molecules to Systems Biology and Drug Design, Wiley, 2007.
• Smith, M. B.; Smith, M., Organic Synthesis, McGraw-Hill, 2001.
• Wuts, P. G. M.; Grene, T. W., Greene´s Protective Groups in Organic Synthesis, 4^th edition, John Wiley & Sons, 2007.